Endocrine Abstracts

The treatment of papillary thyroid cancer consist of surgery and if indicated post-surgical administration of radioiodine with the initiation of thyroid hormone substitution. Whether or not a patient receives a post-operative radioiodine treatment largely depends on the pathological staging (TNM).Through observational data, the benefit of additional radioiodine treatment was only significant in patients with thyroid cancer classified as high risk accordi...

Introduction: (Anti-TNF-α) therapy is widely used for the treatment of inflammatory diseases. The most frequent adverse events induced by anti-TNF-α therapy are infections and malignancies. However, reports of paradoxical sarcoidosis-like reactions are on the rise in patients receiving anti-TNF-α.Clinical case: A 61-year old woman, with a medical history of sero-positive rheumatoid arthritis on Adalimumab treatment (anti-TNF-α), was r...

Introduction: Neurofibromatosis type 1 (NF1) is an autosomal dominant neurocutaneous disorder characterised by the appearance of multiple, mostly benign, tumours throughout the skin and central nervous system. Furthermore, NF1 is associated with a number of (pre)malignant tumours including pheochromocytoma, glioma, invasive breast cancer and (pre)malignant peripheral nerve sheath tumours (1). Approximately 1:2500 to 1:3500 individuals are affected.Medull...

Case: An eighteen-year-old male was forwarded to our department by the ophthalmologist because of the resection of an angiomyxoma of the right eyelid. Medical history included multiple surgically excisions of myxomatous tumors from the skin (gluteal, scapular…). Clinical examination showed some lentiginous lesions on his back and more important clear stigmata of acromegaly (tall stature, wide nose, large hands…). Hence our suspicion of a syndromic disorder, in part...

Background: Thyroid incidentaloma are asymptomatic thyroid nodules that are discovered on an imaging study performed to evaluate other structures. Clinically unrecognized thyroid nodules are common and can be found in up to 50–60% of patients at autopsy.1 Increased use of imaging modalities of better quality in the modern era has resulted in an increased detection of incidental thyroid nodules. The prevalence rate is 67% with ultrasonography (US) imaging, 15% w...

Aims: To determine the impact of antenatal depression on pregnancy outcomes in women with gestational diabetes mellitus (GDM) and women with normal glucose tolerance (NGT).Methods: 1843 women from a Belgian multi-centric prospective cohort study (BEDIP-N Study) received universal screening for GDM with a 75 g OGTT and the IADPSG criteria. The Center for Epidemiologic Studies – Depression (CES-D) questionnaire was completed at the time of the OGTT (b...